Sentinel lymph node biopsy for clinically N0 oral squamous cell carcinoma

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Sentinel lymph node biopsy in N0 squamous cell carcinoma of the oral cavity and oropharynx.

OBJECTIVES To ascertain the feasibility of sentinel lymph node (SLN) localization by preoperative lymphoscintigraphy and intraoperative gamma probe radiolocalization and to determine the predictive value of the SLN for occult metastasis of the neck in N0 squamous cell carcinoma of the oral cavity and oropharynx. DESIGN A prospective study of 20 consecutive patients with N0 squamous cell carci...

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Evaluation of immunohistochemical fine sectioning for sentinel lymph node biopsy in oral squamous cell carcinoma.

OBJECTIVE To determine the level of sentinel lymph node sectioning necessary to accurately detect nodal micrometastasis. STUDY DESIGN Cross-sectional. SETTING Tertiary care university medical center. SUBJECTS AND METHODS Fine sections of oral squamous cell carcinoma sentinel lymph nodes previously sectioned at 2-mm intervals in a prospective clinical trial were reexamined. The results yie...

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Freehand SPECT-guided sentinel lymph node biopsy in early oral squamous cell carcinoma.

BACKGROUND In oral squamous cell carcinoma (OSCC), cervical lymph node status is the most important prognostic factor. Compared to elective neck dissection, reduced morbidity and better quality of life was demonstrated for sentinel lymph node biopsy, which is controversial because of the reduced detection rate of sentinel lymph nodes in close proximity to the injection site (also known as the s...

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Long term results of sentinel lymph node biopsy in early oral squamous cell carcinoma

The objective of the study was to evaluate the long term results of the sentinel node (SN) biopsy technique in the management of the clinically negative (N0) neck in patients with early oral squamous cell carcinoma (T1-T2). Patients with positive SN underwent neck dissection. A sentinel lymph node (SLN) biopsy was performed on 31 consecutive patients. Six of the 31 patients were upstaged by the...

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Clinicopatholgic Parameters Associated With Regional Lymph Node Metastasis In Oral Squamous Cell Carcinoma: A Retrospective Study

  Background and Objective: Oral cancer accounts for less than 3% of all cancers. Despite recent improvement in diagnostic and treatment methods, the overall survival of the disease is unfavorable. Several studies have been performed to assess factors influencing lymph node metastasis and prognosis. The aim of this study was to evaluate some clinical and pathological factors influencing lymph ...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2018

ISSN: 0923-7534

DOI: 10.1093/annonc/mdy287.059